Histamine Receptors as Drug Targets
This book illustrates the current state-of-the-art in histamine research, with a focus on the appropriate methodologies to investigate the pharmacological properties and the therapeutic exploitation of HRs and their ligands. In addition, the range of techniques described provides an introduction to...
| Other Authors: | , |
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| Format: | eBook |
| Language: | English |
| Published: |
New York, NY
Springer New York
2017, 2017
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| Edition: | 1st ed. 2017 |
| Series: | Methods in Pharmacology and Toxicology
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| Subjects: | |
| Online Access: | |
| Collection: | Springer eBooks 2005- - Collection details see MPG.ReNa |
Table of Contents:
- Methodologies to Identify and Analyze Genetic Polymorphisms for Human Histamine Receptors
- Development, Characterization, and Validation of Anti-Human H3 Receptor Isoform-Specific Antibodies
- Approaches to Recombinant Histamine H3/H4 Receptor Expression in Mammalian Cells
- Histamine H2 Receptor Biased Signaling Methods
- Ligand-Binding Kinetics on Histamine Receptors
- Methods to Study the Molecular Pharmacology of the Histamine H4 Receptor
- Chemiluminescence: A Sensitive Method for Detecting the Effects of Histamine Receptor Agonists/Antagonists on Neutrophil Oxidative Burst
- Techniques Used in Pharmacological Evaluation of Histamine H4 Receptor Function on Native Human Eosinophils
- Assessment of the Efficacy of Histamine Receptor Antagonists in Murine Models of Atopic Dermatitis
- Methodological Approaches to Study Histamine Pharmacology in the Kidney: From Cell Culture and Cell Imaging to Functional Assays and Electron Microscopy
- Histamine and the Kidney: In Vivo Animal Models
- Methodological Approaches to Investigate the Effects of Histamine Receptor Targeting Compounds in Preclinical Models of Breast Cancer
- Evaluation of Histidine Decarboxylase (HDC) Activity and Human Histamine Receptor 3 (H3R) and HDC mRNA Levels
- Cerebrospinal Fluid Markers in Neuroinflammation: The Paradigm of Optic Neuritis
- In Vivo Diagnostic Procedures for IgE-Mediated Allergic Disorders
- Dermatological Indications of Antihistamines
- Histamine Quantification in Human Blood Samples