| Summary: | This multi-authored text provides information on the pathophysiology of Gastroesophageal Reflux Disease (GERD), appropriate medical management, and proper indications for and performance of surgical and endoscopic procedures. The Editors look at the current understanding of this disease, and present new information regarding tissue susceptibility, the role of bile and digestive enzymes, and cyclic changes in LES tone. Chapters are devoted to standard therapeutic options for GERD, including lifestyle changes, pharmacologic therapy, and surgery. In addition, newer endoscopic treatments including Stretta, Endocinch, injection of bulking agents, as well as others, are described. Failed Anti-Reflux Therapy: Analysis of Causes and Principles of Treatment is essential to any physician who manages patients with GERD, including internists, gastroenterologists, general surgeons, and thoracic surgeons
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