Immune Infertility Impact of Immune Reactions on Human Fertility

This book offers comprehensive coverage of both basic and clinical aspects of immune reactions responsible for infertility. It has four sections focusing on Sperm antigens, Antisperm antibodies (ASAs), Clinical impact of ASAs, and Immune contraception, and include contributions from leading experts...

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Bibliographic Details
Other Authors: Krause, Walter K.H. (Editor), Naz, Rajesh K. (Editor)
Format: eBook
Language:English
Published: Cham Springer International Publishing 2017, 2017
Edition:2nd ed. 2017
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • Part I Sperm antigens: Proteomics of spermatozoa
  • Sperm surface proteome
  • Methods of Analysis of Sperm Antigens Related to Fertility
  • Sperm functions influenced by immune reactions
  • Part II Antisperm antibodies (ASA): The immune privilege of the testis
  • Immune chemistry of ASA
  • Sperm-specific T cells
  • Site and risk factors of ASA production
  • Biologic substrates containing ASA
  • ASA in the female
  • Sperm immobilising ASA
  • Part III The clinical impact of sperm antibodies: Autoimmune infertility
  • Tests for sperm antibodies
  • Impact on fertility outcome
  • Sperm antibodies and assisted reproduction
  • Treatment of immune infertility
  • Part IV Immune contraception: Immunization with Sperm Antigens to Induce Contraception
  • Immune contraception in wildlife animals
  • Experience from Clinical Trials with Fertility Control Vaccines