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161202 ||| eng |
| 020 |
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|a 9789811025297
|
| 100 |
1 |
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|a Laurent, Sophie
|
| 245 |
0 |
0 |
|a MRI Contrast Agents
|h Elektronische Ressource
|b From Molecules to Particles
|c by Sophie Laurent, Céline Henoumont, Dimitri Stanicki, Sébastien Boutry, Estelle Lipani, Sarah Belaid, Robert N. Muller, Luce Vander Elst
|
| 250 |
|
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|a 1st ed. 2017
|
| 260 |
|
|
|a Singapore
|b Springer Nature Singapore
|c 2017, 2017
|
| 300 |
|
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|a VII, 125 p. 63 illus., 44 illus. in color
|b online resource
|
| 505 |
0 |
|
|a Nanomaterials in medicine -- Magnetic properties (diamagnetism, paramagnetism, ferromagnetism, ferrimagnetism, antiferromagnetism, superparamagnetism) -- Imaging probes -- Magnetic resonance imaging (MRI) -- Bases of MRI -- MRI contrast agents -- Paramagnetic gadolinium complexes -- Superparamagnetic iron oxide nanoparticles -- Synthesis of magnetic nanoparticles -- Stabilization of magnetic nanoparticles -- Physico-chemical characterization of nanoparticles -- MRI applications -- Conclusions
|
| 653 |
|
|
|a Medicine—Research
|
| 653 |
|
|
|a Biology—Research
|
| 653 |
|
|
|a Biomedical engineering
|
| 653 |
|
|
|a Medical physics
|
| 653 |
|
|
|a Biomedical Engineering and Bioengineering
|
| 653 |
|
|
|a Medical Physics
|
| 653 |
|
|
|a Biomedical Research
|
| 653 |
|
|
|a Microtechnology
|
| 653 |
|
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|a Microsystems and MEMS.
|
| 653 |
|
|
|a Biomaterials
|
| 653 |
|
|
|a Microelectromechanical systems
|
| 700 |
1 |
|
|a Henoumont, Céline
|e [author]
|
| 700 |
1 |
|
|a Stanicki, Dimitri
|e [author]
|
| 700 |
1 |
|
|a Boutry, Sébastien
|e [author]
|
| 041 |
0 |
7 |
|a eng
|2 ISO 639-2
|
| 989 |
|
|
|b Springer
|a Springer eBooks 2005-
|
| 490 |
0 |
|
|a Nanotheranostics
|
| 856 |
4 |
0 |
|u https://doi.org/10.1007/978-981-10-2529-7?nosfx=y
|x Verlag
|3 Volltext
|
| 082 |
0 |
|
|a 610.28
|
| 520 |
|
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|a This book describes the multiple aspects of (i) preparation of the magnetic core, (ii) the stabilization with different coatings, (iii) the physico-chemical characterization and (iv) the vectorization to obtain specific nanosystems. Several bio-applications are also presented in this book. In the early days of Magnetic Resonance Imaging (MRI), paramagnetic ions were proposed as contrast agents to enhance the diagnostic quality of MR images. Since then, academic and industrial efforts have been devoted to the development of new and more efficient molecular, supramolecular and nanoparticular systems. Old concepts and theories, like paramagnetic relaxation, were revisited and exploited, leading to new scientific tracks. With their high relaxivity payload, the superparamagnetic nanoparticles are very appealing in the context of molecular imaging but challenges are still numerous: absence of toxicity, specificity, ability to cross the biological barriers, etc.
|