Silicon-mediated transformations of functional groups

In the first work to comprehensively cover this all-important topic, the recognized expert Helmut Vorbruggen provides both organic and bioorganic chemists with much new and valuable information for preparative synthesis. Although every organic chemist may be familiar with different aspects of silyla...

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Main Author: Vorbrüggen, Helmut
Format: eBook
Language:English
Published: Weinheim Wiley-VCH 2004
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Collection: Wiley Online Books - Collection details see MPG.ReNa
Summary:In the first work to comprehensively cover this all-important topic, the recognized expert Helmut Vorbruggen provides both organic and bioorganic chemists with much new and valuable information for preparative synthesis. Although every organic chemist may be familiar with different aspects of silylation for the protection of functional groups, this book covers the concept of protection while simultaneously silylating-activating various functional groups, such as amides and ureas. This novel methodology opens thus numerous synthetic pathways while effecting the elimination of water in it volatile persilylated form under rather mild reaction conditions, which are often advantageous compared to conventional methods. The compact form and clear structure of this monograph make this a long-awaited ready reference.
Physical Description:XII, 364 Seiten
ISBN:9783527306688