Table of Contents:
  • Quality and validity in animal model research are issues of scientific and ethical relevance
  • High-quality research with high validity requires expertise in biological and clinical aspects in combination with knowledge in experimental design
  • Contemporary research using systematic reviews and meta analysis have shown problems with the experimental design of many animal studies
  • As a result of design shortcomings, results from many animal studies are not reliable
  • This lecture addresses basic aspects of quality and validity of animal research using examples