Antiepileptic Drug Discovery Novel Approaches

This thorough volume delves into antiepileptic drug discovery with a comprehensive collection of innovative approaches for the development of antiepileptic therapies, focusing on novel molecular targets for antiepileptic drugs, computer-aided approaches for the identification of new drug candidates,...

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Bibliographic Details
Other Authors: Talevi, Alan (Editor), Rocha, Luisa (Editor)
Format: eBook
Language:English
Published: New York, NY Humana 2016, 2016
Edition:1st ed. 2016
Series:Methods in Pharmacology and Toxicology
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • Inflammatory Cytokines as Targets for Epilepsy Drug Therapy
  • The Use of Anti-Inflammatory Drugs in Epilepsy
  • Carbonic Anhydrase and Epilepsy
  • Synaptic Vesicle Protein 2A as a Novel Pharmacological Target with Broad Potential for New Antiepileptic Drugs
  • Do Cannabinoids Represent a Good Therapeutic Strategy for Epilepsy?
  • Glutamate Receptors as Targets for Novel Antiepileptic Drug Therapy
  • Neurosteroid Regulation of Seizures: Role of GABAA Receptor Plasticity
  • Erythropoietin as Potential Neuroprotective and Antiepileptogenic Agent in Epilepsy and Refractory Epilepsy
  • Caloric Restriction and Dietary Treatments of Epilepsy: Mechanistic Insights for Drug Discovery
  • Gene Therapy in Epilepsy
  • Human Brain Tissue as a Model for the Study of Epilepsy
  • The Blood-Brain Barrier and the Design of New Antiepileptic Drugs
  • Virtual Screening Applications in the Search of Novel Antiepileptic Drug Candidates
  • Discovering New Antiepileptic Drugs Addressing the Transporter Hypothesis of Refractory Epilepsy: Ligand-Based Approximations
  • Discovering New Antiepileptic Drugs Addressing the Transporter Hypothesis of Refractory Epilepsy: Structure-Based Approximations
  • Nanoformulations of Antiepileptic Drugs: In Vitro and In Vivo Studies
  • Side Effects of Antiepileptic Drugs
  • Network Pharmacology and Epilepsy
  • The Importance of Drug Repurposing in the Field of Antiepileptic Drug Development