Protein Tyrosine Phosphatases in Cancer

This book aims to bridge the gap in understanding how protein-tyrosine phosphatases (PTPs), which carry out the reverse reaction of tyrosine phosphorylation, feature in cancer cell biology. The expertly authored chapters will first review the general features of the PTP superfamily, including their...

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Bibliographic Details
Other Authors: Neel, Benjamin G. (Editor), Tonks, Nicholas K. (Editor)
Format: eBook
Language:English
Published: New York, NY Springer New York 2016, 2016
Edition:1st ed. 2016
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • 1 Introduction to the PTP Superfamily
  • 2 Receptor PTPs in Cancer
  • 3 Non-Receptor PTPs in Cancer
  • 4 HP2
  • 5 C-PTP
  • 6 PTP1B
  • 7 PTP-PEST
  • 8 Dual Specificity Phosphatases in Cancer
  • 9 Phosphatase-dependent roles for PTEN in Cancer
  • 10 Phosphatase-independent roles for PTEN in Cancer
  • 11 PRL family members in Cancer
  • 12 Cdc25 family
  • 13 PTPs, metabolism and cancer
  • 14 PTPs, metabolism and cancer
  • 15 Current status of PTP-based therapeutics
  • 16 Summary and Perspective.