The Nuclear Receptor Superfamily Methods and Protocols
This volume aims to describe a complementary range of molecular, cell biological, and in vivo protocols used to investigate the structure–function of nuclear receptors, together with experimental approaches that may lead to new drugs to selectively target nuclear receptor-associated diseases. The Nu...
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| Format: | eBook |
| Language: | English |
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New York, NY
Humana
2016, 2016
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| Edition: | 2nd ed. 2016 |
| Series: | Methods in Molecular Biology
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| Online Access: | |
| Collection: | Springer eBooks 2005- - Collection details see MPG.ReNa |
Table of Contents:
- The Nuclear Receptor Superfamily- At Thirty
- Lipid Homeostasis and Ligands for Liver X Receptors: Identification and Characterization
- Use of Differential Scanning Fluorimetry to Identify Nuclear Receptor Ligands
- Drug-Discovery Pipeline for Novel Inhibitors of the Androgen Receptor
- Use of BRET to Study Protein-Protein Interactions in vitro and in vivo
- Studying Steroid Receptor Complexes in the Cellular Environment
- Post-translational Modifications of Steroid Receptors: Phosphorylation
- Mapping protein-DNA Interactions using ChIP-exo and Illumina-based Sequencing
- Methods to Identify Chromatin Bound Protein Complexes: From Genome-Wide to Locus Specific Approaches
- Measuring the Expression of microRNAs Regulated by Androgens
- Methods for Identifying and Quantifying Mrna Expression of Androgen Receptor Splicing Variants in Prostate Cancer
- Harvesting Human Prostate Tissue Material and Culturing Primary Prostate Epithelial Cells
- In vivo Imaging of Nuclear Receptor Transcriptional Activity
- Development and Characterisation of Cell-Specific Androgen Receptor Knockout Mice