Calcium Entry Pathways in Non-excitable Cells

Calcium entry pathways in non-excitable cells presents a concise synthesis of thoughtfully selected topics covering from the different calcium entry mechanisms in non-excitable cells to the cellular microdomains and organelles regulating the calcium entry process. Particular attention is given to th...

Full description

Bibliographic Details
Other Authors: Rosado, Juan A. (Editor)
Format: eBook
Language:English
Published: Cham Springer International Publishing 2016, 2016
Edition:1st ed. 2016
Series:Advances in Experimental Medicine and Biology
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • Historical overview of store-operated Ca2+ entry
  • The STIM1- Orai interaction
  • The TRPCs, Orais and STIMs in ER/PM junctions
  • The TRP-Na-Ca2+ exchanger coupling
  • Role of TRPC channels in store-operated calcium entry
  • Phospholipase A2 as a molecular determinant of store-operated calcium entry
  • Extracellular calcium has multiple targets to control cell proliferation
  • Regulation of platelet function by Orai, STIM and TRP
  • On the roles of the Transient Receptor Potential Canonical 3 (TRPC3) channel in endothelium and macrophages: implications in atherosclerosis
  • Second messenger-operated calcium entry through TRPC6
  • Transient Receptor Potential Canonical 7 (TRPC7), a Calcium (Ca2+) Permeable Nonselective Cation Channel
  • Calcium entry through thermosensory channels
  • Calcium signalling through ligand-gated ion channels such as P2X1 receptors in the platelet and other non-excitable cells
  • The calcium entry-calcium refilling coupling
  • Microdomains associated to lipid rafts
  • Role of scaffolding proteins in the regulation of TRPC-dependent calcium entry
  • Modulation of calcium entry by mitochondria
  • Modulation of calcium entry by the endo-lysosomal system
  • Remodeling of calcium entry pathways in cancer