Myeloid-Derived Suppressor Cells and Cancer

The book starts with an introduction to and history of myeloid-derived suppressor cells (MDSCs), followed by a description of their differentiation, their role in the tumour microenvironment and their therapeutic targeting. It closes with an outlook on future developments. In cancer patients, myelop...

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Bibliographic Details
Main Authors: Escors, David, Talmadge, James E. (Author), Breckpot, Karine (Author), Van Ginderachter, Jo A. (Author)
Format: eBook
Language:English
Published: Cham Springer International Publishing 2016, 2016
Edition:1st ed. 2016
Series:SpringerBriefs in Immunology
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • Controversies in Neoplastic Myeloplasia
  • Differentiation of Murine Myeloid-derived Suppressor Cells
  • Human MDSCs
  • Ex Vivo MDSC Differentiation Models
  • Immunoregulatory myeloid cells in the tumor microenvironment
  • Signal Transducer and Activation of Transcription 3: A Master Regulator of Myeloid-derived Suppressor Cells
  • Future Perspectives