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Antisense oligonucleotides the promise and the problems

Bibliographic Details
Main Author: Frazier, Kendall S.
Format: eBook
Language:English
Published: London Henry Stewart Talks 2015, 2015
Series:Future directions in therapeutic intervention, diagnostics and prophylactics
Subjects:
Toxicity Tests
Patient Safety
Drug Discovery / Methods
Oligonucleotides, Antisense / Toxicity
Antisense Nucleic Acids
Oligonucleotides, Antisense / Adverse Effects
Oligonucleotides, Antisense / Therapeutic Use
Drug Development
Toxicity Testing
Online Access:
Collection: Henry Stewart Talks - Collection details see MPG.ReNa
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300 |a 1 online resource (1 streaming video file (45 min.)  |b color, sound) 
505 0 |a Antisense oligonucleotide (ASOs) therapies -- Screening strategies for drug candidates -- Locked nucleic acid (LNA) gapmers -- Understanding off-target effects (OTEs) -- Mechanisms of ASO toxicity and clinical relevance -- New targets/delivery systems under development 
653 |a Toxicity Tests 
653 |a Patient Safety 
653 |a Drug Discovery / methods 
653 |a Oligonucleotides, Antisense / toxicity 
653 |a Antisense nucleic acids 
653 |a Oligonucleotides, Antisense / adverse effects 
653 |a Oligonucleotides, Antisense / therapeutic use 
653 |a Drug development 
653 |a Toxicity testing 
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490 0 |a Future directions in therapeutic intervention, diagnostics and prophylactics 
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