ABC Transporters - 40 Years on

This book provides new structural, biochemical, and clinical information on ABC transporters. The authors explore and describe the state of the art of research, knowledge, and prospects for the future for this important family of proteins. The first ABC transporter was discovered in 1973 and was nam...

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Bibliographic Details
Other Authors: George, Anthony M. (Editor)
Format: eBook
Language:English
Published: Cham Springer International Publishing 2016, 2016
Edition:1st ed. 2016
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • ABC Importers
  • Inborn errors and potential correction of the cellular expression and localization of medically important ABC transporters
  • Human ABC transporter ABCC11: Molecular mechanistic, pharmacological, and anthropological aspects
  • Biology of mitochondrial ABCs and their contribution to pathology
  • ABC transporters and multidrug resistance in fungi and yeast
  • Structural and mechanistic insights into modulation of P-glycoprotein (ABCB1)function by tyrosine kinase inhibitors
  • Techniques for the purification of ABC transporters
  • HDAC inhibitors and MDR ABC transporters
  • The role of polymorphisms in P-glycoprotein (ABCB1) on function
  • Interaction of ABC transporters with drugs
  • ABC insights from CFTR.