Mathematical Analysis of Complex Cellular Activity

This book contains two review articles on mathematical physiology that deal with closely related topics but were written and can be read independently. The first article reviews the basic theory of calcium oscillations (common to almost all cell types), including spatio-temporal behaviors such as wa...

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Bibliographic Details
Main Authors: Bertram, Richard, Tabak, Joel (Author), Teka, Wondimu (Author), Vo, Theodore (Author)
Format: eBook
Language:English
Published: Cham Springer International Publishing 2015, 2015
Edition:1st ed. 2015
Series:Frontiers in Applied Dynamical Systems: Reviews and Tutorials
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
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245 0 0 |a Mathematical Analysis of Complex Cellular Activity  |h Elektronische Ressource  |c by Richard Bertram, Joel Tabak, Wondimu Teka, Theodore Vo, Martin Wechselberger, Vivien Kirk, James Sneyd 
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505 0 |a Preface -- Bursting Oscillations in Pituitary Cells: Z-Curves, Folded Nodes, Calcium Stores and Mixed-Mode Oscillations -- The Nonlinear Dynamics of Calcium 
653 |a Dynamical Systems and Ergodic Theory 
653 |a Ergodic theory 
653 |a Statistical physics 
653 |a Biomathematics 
653 |a Physiological, Cellular and Medical Topics 
653 |a Applications of Nonlinear Dynamics and Chaos Theory 
653 |a Dynamics 
700 1 |a Tabak, Joel  |e [author] 
700 1 |a Teka, Wondimu  |e [author] 
700 1 |a Vo, Theodore  |e [author] 
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520 |a This book contains two review articles on mathematical physiology that deal with closely related topics but were written and can be read independently. The first article reviews the basic theory of calcium oscillations (common to almost all cell types), including spatio-temporal behaviors such as waves. The second article uses, and expands on, much of this basic theory to show how the interaction of cytosolic calcium oscillators with membrane ion channels can result in highly complex patterns of electrical spiking. Through these examples one can see clearly how multiple oscillatory processes interact within a cell, and how mathematical methods can be used to understand such interactions better. The two reviews provide excellent examples of how mathematics and physiology can learn from each other, and work jointly towards a better understanding of complex cellular processes. Review 1: Richard Bertram, Joel Tabak, Wondimu Teka, Theodore Vo, Martin Wechselberger: Geometric Singular Perturbation Analysis of Bursting Oscillations in Pituitary Cells Review 2: Vivien Kirk, James Sneyd: The Nonlinear Dynamics of Calcium