Overcoming resistance through novel drug targets

Bibliographic Details
Main Author: Coates, Anthony R. M.
Format: eBook
Language:English
Published: London Henry Stewart Talks 2009, 2009
Series:Antibiotic resistance : from genes to global prevalence
Subjects:
Online Access:
Collection: Henry Stewart Talks - Collection details see MPG.ReNa
Table of Contents:
  • Urgent need for new antibiotics
  • Why are so few antibiotics reaching the market
  • Pharmaceutical companies leaving the research arena
  • Targets
  • Bacterial molecules (genomics)
  • Problems with the genomic approach
  • Bacteriophage
  • Treatments and problems with bacteriophages
  • Whole bacteria
  • Conventional multiplying bacteria
  • Non-culturable bacteria
  • Non-multiplying bacteria
  • Tuberculosis, bacterial endocarditis, catheter infections and prosthesis infections
  • Ways of making new antibiotics against whole live bacteria
  • Potential advantages and problems of making new antibiotics which kill non-multiplying and multiplying bacteria
  • Standardization