|
|
|
|
LEADER |
02259nmm a2200277 u 4500 |
001 |
EB001083451 |
003 |
EBX01000000000000000842858 |
005 |
00000000000000.0 |
007 |
cr||||||||||||||||||||| |
008 |
151019 ||| eng |
100 |
1 |
|
|a Tofilon, Philip J.
|
245 |
0 |
0 |
|a Global analysis of gene translation
|h Elektronische Ressource
|c Philip Tofilon
|
260 |
|
|
|a London
|b Henry Stewart Talks
|c 2009, 2009
|
300 |
|
|
|a 1 online resource (1 streaming video file (38 min.)
|b color, sound)
|
505 |
0 |
|
|a Radiation-induced gene expression has long been considered to play a role in determining cellular radioresponse -- Analyses of single genes and whole genomes indicate that radiation-induced changes at the mRNA level do not correlate with changes in corresponding proteins -- Microarray analysis of polysome-bound RNA indicates that radiation modifies the translational activity of mRNA subpopulations, which correlates with protein products -- Gene translation is considerably more susceptible to radiation-induced changes than is the transcriptome -- Defining the genes whose translation is modified by radiation may provide an approach for identifying critical proteins and pathways that serve as determinants of radiosensitivity
|
653 |
|
|
|a Protein Biosynthesis / radiation effects
|
653 |
|
|
|a Gene Expression
|
653 |
|
|
|a Oligonucleotide Array Sequence Analysis
|
653 |
|
|
|a Microarray Analysis
|
041 |
0 |
7 |
|a eng
|2 ISO 639-2
|
989 |
|
|
|b HST
|a Henry Stewart Talks
|
490 |
0 |
|
|a Microarrays : their design and use
|
500 |
|
|
|a Animated audio-visual presentation with synchronized narration. - Title from title frames. - Mode of access: World Wide Web. - System requirements: Browser compatibility: updated Mozilla Firefox, Google Chrome, Safari or Internet Explorer 8+. Browser settings: enable JavaScript, enable cookies from the Henry Stewart Talks site. Required Desktop Browser plugins & viewers: Updated Adobe Flash Player & Adobe Acrobat Reader. Mobile device & operating system versions: Android v4.0+, iPhone 4+ (iOS v6.x+), iPad 2+ (iOS v6.x+), BlackBerry OS v7.0+, Windows Phone v6.5.1+
|
856 |
4 |
2 |
|u https://hstalks.com/bs/p/382
|3 Series
|
856 |
4 |
0 |
|u https://hstalks.com/bs/1201
|x Verlag
|z Streaming video file
|
082 |
0 |
|
|a 570
|