Global analysis of gene translation

Bibliographic Details
Main Author: Tofilon, Philip J.
Format: eBook
Language:English
Published: London Henry Stewart Talks 2009, 2009
Series:Microarrays : their design and use
Subjects:
Online Access:
Collection: Henry Stewart Talks - Collection details see MPG.ReNa
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100 1 |a Tofilon, Philip J. 
245 0 0 |a Global analysis of gene translation  |h Elektronische Ressource  |c Philip Tofilon 
260 |a London  |b Henry Stewart Talks  |c 2009, 2009 
300 |a 1 online resource (1 streaming video file (38 min.)  |b color, sound) 
505 0 |a Radiation-induced gene expression has long been considered to play a role in determining cellular radioresponse -- Analyses of single genes and whole genomes indicate that radiation-induced changes at the mRNA level do not correlate with changes in corresponding proteins -- Microarray analysis of polysome-bound RNA indicates that radiation modifies the translational activity of mRNA subpopulations, which correlates with protein products -- Gene translation is considerably more susceptible to radiation-induced changes than is the transcriptome -- Defining the genes whose translation is modified by radiation may provide an approach for identifying critical proteins and pathways that serve as determinants of radiosensitivity 
653 |a Protein Biosynthesis / radiation effects 
653 |a Gene Expression 
653 |a Oligonucleotide Array Sequence Analysis 
653 |a Microarray Analysis 
041 0 7 |a eng  |2 ISO 639-2 
989 |b HST  |a Henry Stewart Talks 
490 0 |a Microarrays : their design and use 
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856 4 0 |u https://hstalks.com/bs/1201  |x Verlag  |z Streaming video file 
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