Replication licensing
| Main Author: | |
|---|---|
| Format: | eBook |
| Language: | English |
| Published: |
London
Henry Stewart Talks
2009, 2009
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| Series: | The cell division cycle : controlling when and where cells divide and differentiate
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| Subjects: | |
| Online Access: | |
| Collection: | Henry Stewart Talks - Collection details see MPG.ReNa |
Table of Contents:
- Problems in ensuring complete genome replication
- Experiments revealing the existence of a replication licence
- The licensing reaction
- ORC, Cdc6, Cdt1 and Mcm2-7
- Cell cycle regulation of licensing
- Pre-RC substrates in yeast
- Regulation of licensing in animal cells by Cdt1 degradation and geminin inhibition
- Is there a licensing checkpoint?
- Replication licensing and cancer
- The "MCM paradox" and dormant replication origins
- The licensing system as a potential anti-cancer target