Chromosome bi-orientation in yeast
| Main Author: | |
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| Format: | eBook |
| Language: | English |
| Published: |
London
Henry Stewart Talks
2009, 2009
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| Series: | The cell division cycle : controlling when and where cells divide and differentiate
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| Subjects: | |
| Online Access: | |
| Collection: | Henry Stewart Talks - Collection details see MPG.ReNa |
Table of Contents:
- What is chromosome biorientation and why is it important?
- Failure to bi-orient a chromosome will lead to mis-segregation/aneuploidy
- Modes of sister chromatid attachment to spindle microtubules
- The budding yeast (Saccharomyces cerevisiae) as a model for studying chromosome bi-orientation
- Monitoring sister centromeres on individual yeast chromosomes
- Kinetochore capture
- Achieving chromosome bi-orientation: mechanisms
- Geometry-dependent mechanism or a correction mechanism?
- Yeast Ipl1p kinase
- Chromosomes fail to bi-orient with high frequency in Ipl1 mutants
- How might Ipl1p kinase promote bi-orientation?
- Yeast chromosomes can bi-orient without the need for back-to-back geometry
- How does Ipl1p kinase promote bi-orientation?
- The yeast chromosomal passenger complex
- Models for tension-sensing
- What are the targets of Ipl1p kinase at the kinetochore?
- Model for Ipl1 / Aurora function in promoting bi-orientation