Translocational applications of cardiovascular genomics opportunities and challenges
| Main Author: | |
|---|---|
| Format: | eBook |
| Language: | English |
| Published: |
London
Henry Stewart Talks
2008, 2008
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| Series: | Genetics of cardiovascular disease : genetic interactions in a multifactorial disease
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| Subjects: | |
| Online Access: | |
| Collection: | Henry Stewart Talks - Collection details see MPG.ReNa |
Table of Contents:
- Ischaemic heart disease
- Valvular heart disease
- Heart muscle disease
- Monogenic form of common disorder
- Single gene disorders and cardiovascular disease
- Mutation both necessary and sufficient to lead to disease
- Genetic basis of the common form of CHD
- Polygenic form of common disorder
- Complex disorders
- Study design
- Candidate genes or whole genome
- Genome-wide association studies
- A new dawn for genetics of complex disorders and traits
- Relationship between allele frequency and effect size
- Genetic architecture of common disease
- Translation of genomic discoveries
- Potential advantages of genetic tests
- Predictive genetic screening for CHD
- Low penetrance polymorphisms
- Multiple risk alleles
- Why genetic testing might perform poorly as a discriminatory test
- Genotype and prediction of CHD
- Using genotype to gain insight into the causes of CHD
- Unique properties of genotype