Bevacizumab the first FDA-approved angiogenesis inhibitor in the treatment of non-small cell lung cancer
Main Author: | |
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Format: | eBook |
Language: | English |
Published: |
London
Henry Stewart Talks
2009, 2009
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Series: | Cancer therapy : latest thinking in efficacy and toxicity
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Subjects: | |
Online Access: | |
Collection: | Henry Stewart Talks - Collection details see MPG.ReNa |
Table of Contents:
- Lung cancer incidence
- Survival by treatment group
- Selected trials of novel agents + chemotherapy
- Bevacizumab
- Vascular Endothelial Growth Factor (VEGF)
- Principles of angiogenesis
- Bevacizumab in NSCLC: not for everybody
- Randomized phase II trial of Paclitaxel/Carboplatin with/without Bevacizumab in NSCLC
- Hemorrhagic events
- Example of tumor cavitation in lung following treatment with chemotherapy and Bevacizumab
- Patient haracteristics
- Response rates
- Hematologic and non-hematologic toxicity
- Treatment related deaths
- Efficacy by gender and age
- NCCN pactice guidelines in oncology-v.2.2008
- AVAiL: phase III trial of Bevacizumab + Gemcitabine and Cisplatin in advanced non|squamous cell NSCLC
- Second line therapy for advanced NSCLC: the role of Bevacizumab
- Adjuvant therapy in NSCLC
- Can a broader range of patients be safely treated with Bevacizumab?
- Protocol AVF3744g: BRIDGE trial