Chemical synthesis of peptides and peptide libraries
| Main Author: | |
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| Format: | eBook |
| Language: | English |
| Published: |
London
Henry Stewart Talks
2022, 2022
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| Series: | Chemical biology : the role of chemistry in our fundamental understanding of biology
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| Subjects: | |
| Online Access: | |
| Collection: | Henry Stewart Talks - Collection details see MPG.ReNa |
Table of Contents:
- Contents: Peptide and protein synthesis is the most robust of all synthetic chemistries
- Very large combinatorial libraries with billions of different peptides are possible
- Highly constrained peptides with specific secondary (phi/psi space) and tertiary (chi space) structures can be designed and synthesized
- Peptides stable to proteolytic degradation and able to cross BBB can be synthesized
- Peptides designed and synthesized with potent and selective bioactivities
- Many excellent drugs
- Peptide synthesis a critical tool for all aspects of chemical biology