Oxidative stress in ALS

Bibliographic Details
Main Author: Shaw, Pamela J.
Format: eBook
Language:English
Published: London Henry Stewart Talks 2007, 2007
Series:Free radicals and the oxygen paradox : oxidative stress in biology, aging and disease
Subjects:
Online Access:
Collection: Henry Stewart Talks - Collection details see MPG.ReNa
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100 1 |a Shaw, Pamela J. 
245 0 0 |a Oxidative stress in ALS  |h Elektronische Ressource  |c Pam Shaw 
260 |a London  |b Henry Stewart Talks  |c 2007, 2007 
300 |a 1 online resource (1 streaming video file (58 min.)  |b color, sound) 
505 0 |a Key facts -- The normal human motor system -- Motor neurone disease: clinical consequences -- Spared motor neurone groups -- Prognosis -- Features of motor neurones which may underlie selective vulnerability -- Complex and multifactorial disease -- Genetic factors -- SOD1 mutations -- Potential mechanisms of neuronal oxidative stress -- Sources of intracellular oxidative stress -- Mitochondrial free radical production -- ROS -- Evidence for the role of oxidative stress in ALS -- NSC34 cell model -- G93A mutant SOD1 -- Oxidative stress in human ALS -- Major pathogenetic factors -- Glutamate -- Excitotoxicity -- Mitochondrial dysfunction -- Potential mechanisms of action of antioxidant drugs -- Clinical trials 
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653 |a Oxidative Stress 
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490 0 |a Free radicals and the oxygen paradox : oxidative stress in biology, aging and disease 
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