The endoplasmic reticulum the unfolded protein response
| Main Author: | |
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| Format: | eBook |
| Language: | English |
| Published: |
London
Henry Stewart Talks
2007, 2007
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| Series: | The endoplasmic reticulum : fundamentals and role in disease
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| Subjects: | |
| Online Access: | |
| Collection: | Henry Stewart Talks - Collection details see MPG.ReNa |
Table of Contents:
- The secretory pathway
- Factor VIII expression induces ER stress
- Protein folding: the ultimate and most error prone step in gene expression
- The "unfolded protein response" (UPR) ensures fidelity of protein folding
- UPR signaling response
- Activation of the UPR
- Stress signaling from the ER
- Role of eIF2 in translation initiation
- Translation initiation response to external stimuli
- eIF2a phosphorylation is required for UPR
- Wolcott-Rallison syndrome
- Plasma cell differentiation requires ER expansion
- Roles of IRE1a/XBP1 in lymphocyte development
- ER-stress-induced transcription through regulated intramembrane proteolysis (RIP)
- CREBH and ATF6
- ER-stress-induced apoptosis
- ER stress and oxidative stress
- UPR-induced alterations in gene expression