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008 151019 ||| eng
100 1 |a Feldmann, Marc 
245 0 0 |a Anti TNF therapy in rheumatoid arthritis  |h Elektronische Ressource  |c Marc Feldmann 
246 3 1 |a Anti-TNF therapy in rheumatoid arthritis 
260 |a London  |b Henry Stewart Talks  |c 2007, 2007 
300 |a 1 online resource (1 streaming video file (58 min.)  |b color, sound) 
505 0 |a Immunological basis of rheumatoid arthritis (RA) -- Up-regulated cytokine expression is of major importance in RA -- Analysis of the disordered regulation shows that TNF blockade restored normal cytokine and destructive molecule levels and thus defined TNF as a therapeutic target -- Animal models of arthritis -- Clinical trials -- TNF has major input into leucocyte recruitment, it is thus the body's fire alarm -- TNF blockade and Crohn's disease, ulcerative colitis, ankylosing spondylitis, psoriasis, psoriatic arthritis and juvenile RA -- This represents the first major use for monoclonal antibodies in chronic diseases 
653 |a Arthritis, Rheumatoid / immunology 
653 |a Tumor Necrosis Factor-alpha / therapeutic use 
653 |a Antibodies, Monoclonal / therapeutic use 
653 |a Arthritis, Rheumatoid 
653 |a Arthritis, Rheumatoid / therapy 
653 |a Tumor Necrosis Factor-alpha 
041 0 7 |a eng  |2 ISO 639-2 
989 |b HST  |a Henry Stewart Talks 
490 0 |a Monoclonal antibodies as therapeutic agents : fundamentals, therapeutic applications and latest advances 
500 |a Animated audio-visual presentation with synchronized narration. - Title from title frames. - Mode of access: World Wide Web. - System requirements: Browser compatibility: updated Mozilla Firefox, Google Chrome, Safari or Internet Explorer 8+. Browser settings: enable JavaScript, enable cookies from the Henry Stewart Talks site. Required Desktop Browser plugins & viewers: Updated Adobe Flash Player & Adobe Acrobat Reader. Mobile device & operating system versions: Android v4.0+, iPhone 4+ (iOS v6.x+), iPad 2+ (iOS v6.x+), BlackBerry OS v7.0+, Windows Phone v6.5.1+ 
856 4 2 |u https://hstalks.com/bs/p/30  |3 Series 
856 4 0 |u https://hstalks.com/bs/593  |x Verlag  |z Streaming video file 
082 0 |a 570