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02297nmm a2200265 u 4500 |
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EB001082674 |
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EBX01000000000000000842081 |
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00000000000000.0 |
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cr||||||||||||||||||||| |
| 008 |
151019 ||| eng |
| 100 |
1 |
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|a Dobson, C. M.
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| 245 |
0 |
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|a Protein folding and misfolding
|h Elektronische Ressource
|b from theory to therapy
|c Christopher M. Dobson
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| 260 |
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|a London
|b Henry Stewart Talks
|c 2007, 2007
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| 300 |
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|a 1 online resource (1 streaming video file (69 min.)
|b color, sound)
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| 505 |
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|a Protein nature, folding and complexity -- Folding in a cellular environment -- The underlying principles of folding -- Native and transition states -- Exploring the energy surface -- The folding of lysozyme -- The consequences of protein misfolding -- The relationship between folding and disease -- Protein deposition diseases -- Protein aggregates in amyloid diseases -- Amyloidogenic mutations of lysozyme -- Mechanism of amyloid formation -- Structure of the amyloidogenic intermediate -- Amyloid formation by lysozyme in vivo -- SH3 domain of PI3 kinase -- Model of an amyloid fibril -- The underlying origins of amyloid disease -- Generic toxicity of amyloid aggregates -- Cellular defences against aggregation -- Evolutionary design of proteins -- "Post-evolutionary" diseases
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| 653 |
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|a Proteins
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| 653 |
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|a Protein Conformation
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| 653 |
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|a Protein Folding
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| 041 |
0 |
7 |
|a eng
|2 ISO 639-2
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| 989 |
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|b HST
|a Henry Stewart Talks
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| 490 |
0 |
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|a Protein folding, aggregation and design : concepts, experiments, theories and mechanisms
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| 500 |
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|a Animated audio-visual presentation with synchronized narration. - Title from title frames. - Mode of access: World Wide Web. - System requirements: Browser compatibility: updated Mozilla Firefox, Google Chrome, Safari or Internet Explorer 8+. Browser settings: enable JavaScript, enable cookies from the Henry Stewart Talks site. Required Desktop Browser plugins & viewers: Updated Adobe Flash Player & Adobe Acrobat Reader. Mobile device & operating system versions: Android v4.0+, iPhone 4+ (iOS v6.x+), iPad 2+ (iOS v6.x+), BlackBerry OS v7.0+, Windows Phone v6.5.1+
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| 856 |
4 |
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|u https://hstalks.com/bs/429
|x Verlag
|z Streaming video file
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| 856 |
4 |
2 |
|u https://hstalks.com/bs/p/34
|3 Series
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| 082 |
0 |
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|a 570
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