Table of Contents:
  • PLC-gamma in growth factor signaling
  • PLC-gamma as an enzyme
  • Substrate and products
  • PLC family members
  • Domains
  • Association of PLC-gamma with activated receptor tyrosine kinases and membranes
  • Tyrosine phosphorylation sites of PLC-gamma
  • PLC-gamma1 verses PLC-gamma2
  • Measurement of protein and enzymatic activation
  • Downstream signaling by PLC-gamma in T cells
  • PLC-gamma mediation of integrins during adhesion and spreading
  • PLC-gamma biologic roles