Table of Contents:
  • Understanding the origins of nucleotide driven conformational change
  • Molecular motors powered by ATP
  • ATPases belonging to the AAA protein family
  • PspF from E.coli
  • Phage shock genes
  • ATP transition state analogue ADPAlF
  • X-ray crystallographic structural analysis
  • Initiation of conformational changes
  • Role of structural changes in sigma54 subunit
  • Formation of open promoter complexes
  • Changes in DNA binding properties of sigma54
  • Structural organisation of the RNAP holoenzyme