The interplay between protein phosphorylation and ubiquitylation in the NF-ĸB pathway

Bibliographic Details
Main Author: Chen, Zhijian 'James'
Format: eBook
Language:English
Published: London Henry Stewart Talks 2010, 2010
Series:Protein phosphorylation
Subjects:
Online Access:
Collection: Henry Stewart Talks - Collection details see MPG.ReNa
Table of Contents:
  • Ubiquitination is a reversible covalent modification, akin to phosphorylation
  • Ubiquitination regulates protein kinase activity through proteasome-independent mechanisms
  • K63-linked polyubiquitination activates TAK1 and IKK in the NF-kappaB pathway
  • Deubiquitination enzymes inhibit protein kinases in the NF-kappaB pathway
  • Protein kinase regulation by ubiquitin is important in innate and adaptive immunity