Cellular cofactors of HIV integrase from target identification to discovery of ledgins

Bibliographic Details
Main Author: Debyser, Zeger
Format: eBook
Language:English
Published: London Henry Stewart Talks 2011, 2011
Series:Antivirals : latest developments and future progress
Subjects:
Online Access:
Collection: Henry Stewart Talks - Collection details see MPG.ReNa
Table of Contents:
  • Cellular cofactors of HIV as novel antiviral targets
  • LEDGF/p75 is a tethering factor of HIV integrase
  • Identification of LEDGF/p75 as binding partner of integrase
  • Characterization of the interaction
  • Validation of integrase
  • LEDGF/p75 interaction as antiviral target
  • Assay and Drug Development
  • Transportin
  • SR2 is a nuclear import factor