Network motifs basic building blocks of biological networks

Bibliographic Details
Main Author: Alon, Uri
Format: eBook
Language:English
Published: London Henry Stewart Talks 2012, 2012
Series:Protein homeostasis : folding proteins and maintaining the protein-protein interaction networks
Subjects:
Online Access:
Collection: Henry Stewart Talks - Collection details see MPG.ReNa
Table of Contents:
  • Complex networks are found throughout biology
  • Can we define the basic building blocks of networks?
  • Database of direct transcription interactions in E. coli
  • Algorithm that finds n-node network motifs
  • Feedforward loop (FFL)
  • Dynamics of the feed-forward loop system
  • The feed-forward loop is a filter for transient signals allowing fast shutdown
  • GFP reporter plasmid system for promoter activity
  • Response to brief pulses of X is filtered by FFL
  • Sign-sensitive filtering by arabinose feed-forward loop
  • Single input module (SIM)
  • Dense overlapping regulons (DOR)
  • Incoherent FFL is a pulse generator
  • Network motifs in human organ development
  • Network motifs in growth factor signalling
  • High-accuracy promoter activity measurements in living cells