Physiology and pathophysiology of microglia
| Main Author: | |
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| Format: | eBook |
| Language: | English |
| Published: |
London
Henry Stewart Talks
2012, 2012
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| Series: | Physiology and pathophysiology of neuroglia : roles in health and disease
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| Subjects: | |
| Online Access: | |
| Collection: | Henry Stewart Talks - Collection details see MPG.ReNa |
Table of Contents:
- Physiology and pathophysiology of microglia
- Microglia
- resident innate immune cells of the CNS
- Approaches to the study of microglia
- Developmental origin and functions
- Developmental contributions and consequences of malfunction
- The concept of 'resting' microglia
- functions in the healthy adult CNS
- Tissue surveillance and synaptic nursing as house-keeping duties
- The concept of microglial 'activation'
- transformation to distinct activity states
- The concept of detrimental microglia
- Activation signals and response diversity
- Macrophages and microglia: diversity in response behaviour
- Elements of the microglial response repertoire
- Response dynamics
- Microglial phenotypes associated with phagocytosis
- Contributions of microglia in neurodegenerative diseases