Dendritic cells in asthma
Main Author: | |
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Format: | eBook |
Language: | English |
Published: |
London
Henry Stewart Talks
2013, 2013
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Series: | Advances in asthma : new mechanisms, management strategies and treatments
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Subjects: | |
Online Access: | |
Collection: | Henry Stewart Talks - Collection details see MPG.ReNa |
Table of Contents:
- The global immune response of the lungs
- Dendritic cells (DCs): localisation, trafficking, probing for antigen, activation, behaviour in airways during asthma and inflammation
- Controlling responsiveness to the node T cell area & Immunological synapse formation
- Peptide presentation by MHC class II molecules
- Cascade of costimulatory events
- Th2 lymphocytes role in airway inflammation
- Targeting DCs
- Allergen exposure activation
- Epithelial vs. DC expression of TLR4
- Metabolic alterations
- Uric acid and antigen sensitisation in mice
- DC depletion
- Basement membrane thickening in asthma
- Model of chronic airway remodelling in the lungs
- Collagen deposition & antigen uptake/recognition
- Presentation of neoantigen