Dendritic cells in asthma

Bibliographic Details
Main Author: Lambrecht, Bart N.
Format: eBook
Language:English
Published: London Henry Stewart Talks 2013, 2013
Series:Advances in asthma : new mechanisms, management strategies and treatments
Subjects:
Online Access:
Collection: Henry Stewart Talks - Collection details see MPG.ReNa
Table of Contents:
  • The global immune response of the lungs
  • Dendritic cells (DCs): localisation, trafficking, probing for antigen, activation, behaviour in airways during asthma and inflammation
  • Controlling responsiveness to the node T cell area & Immunological synapse formation
  • Peptide presentation by MHC class II molecules
  • Cascade of costimulatory events
  • Th2 lymphocytes role in airway inflammation
  • Targeting DCs
  • Allergen exposure activation
  • Epithelial vs. DC expression of TLR4
  • Metabolic alterations
  • Uric acid and antigen sensitisation in mice
  • DC depletion
  • Basement membrane thickening in asthma
  • Model of chronic airway remodelling in the lungs
  • Collagen deposition & antigen uptake/recognition
  • Presentation of neoantigen