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008 151019 ||| eng
100 1 |a Copeland, Robert Allen 
245 0 0 |a Enzymology in drug discovery  |h Elektronische Ressource  |b part 2 of 2  |c Robert A. Copeland 
246 3 1 |a Enzymology in drug discovery part, part 2 of 2 
260 |a London  |b Henry Stewart Talks  |c 2013, 2013 
300 |a 1 online resource (1 streaming video file (66 min.)  |b color, sound) 
505 0 |a Enzymes as targets for drug discovery -- Protein-ligand binding equilibria -- Enzyme reaction mechanisms -- Structure and function of enzyme active sites -- Measuring enzyme velocity in the laboratory -- Reversible modes of enzyme inhibition -- Enzyme inhibition as a mechanism of pharmacological intervention in disease -- Clinical value of different inhibition modalities -- Non-classical inhibition -- Enzyme assays and screening criteria -- Lead optimization -- Summary: basic information to look for 
653 |a Pharmaceutical chemistry 
653 |a Enzyme Inhibitors / pharmacology 
653 |a Enzymes 
653 |a Drug Discovery 
653 |a Enzyme Inhibitors / chemistry 
653 |a Enzyme inhibitors / Structure-activity relationships 
653 |a Enzyme Inhibitors / metabolism 
653 |a Enzyme Inhibitors / therapeutic use 
653 |a Drug Design 
653 |a Enzymology 
653 |a Drugs / Design 
653 |a Enzyme inhibitors / Therapeutic use 
041 0 7 |a eng  |2 ISO 639-2 
989 |b HST  |a Henry Stewart Talks 
490 0 |a Small molecule drug discovery 
500 |a Animated audio-visual presentation with synchronized narration. - Title from title frames. - Mode of access: World Wide Web. - System requirements: Browser compatibility: updated Mozilla Firefox, Google Chrome, Safari or Internet Explorer 8+. Browser settings: enable JavaScript, enable cookies from the Henry Stewart Talks site. Required Desktop Browser plugins & viewers: Updated Adobe Flash Player & Adobe Acrobat Reader. Mobile device & operating system versions: Android v4.0+, iPhone 4+ (iOS v6.x+), iPad 2+ (iOS v6.x+), BlackBerry OS v7.0+, Windows Phone v6.5.1+ 
856 4 0 |u https://hstalks.com/bs/2638  |x Verlag  |z Streaming video file 
856 4 2 |u https://hstalks.com/bs/p/739  |3 Series 
082 0 |a 570