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Genome scans for hypertension

Bibliographic Details
Main Author: Munroe, Patricia
Format: eBook
Language:English
Published: London Henry Stewart Talks 2014, 2014
Series:Genetics of cardiovascular disease : genetic interactions in a multifactorial disease
Subjects:
Hypertension / Drug Therapy
Genetic Linkage
Hypertension / Epidemiology
Genome-wide Association Study
Cardiovascular Diseases / Drug Therapy
Hypertension / Genetics
Cardiovascular Diseases / Genetics
Hypertension / Etiology
Hypertension / Genetic Aspects
Medical Genetics
Cardiovascular System / Diseases / Genetic Aspects
Online Access:
Collection: Henry Stewart Talks - Collection details see MPG.ReNa
Table of Contents:
  • Hypertension: cause of 4.5% of global disease burden
  • Causes of hypertension
  • Complex trait: multiple risk factors
  • Strategies for finding genes
  • Candidate gene analysis
  • Genome-wide scans
  • Blood pressure traits
  • Genes with major effects?
  • Linkage analyses
  • Monogenic forms of hypertension linkage results
  • Human chromosomes showing regions of linkage with hypertension
  • Interpretation
  • Little consistency between studies
  • Other methodological approaches are required

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