Autosomal recessive Parkinson's disease and mitophagy
Main Author: | |
---|---|
Format: | eBook |
Language: | English |
Published: |
London
Henry Stewart Talks
2014, 2014
|
Series: | The genetic basis of neurological disorders
|
Subjects: | |
Online Access: | |
Collection: | Henry Stewart Talks - Collection details see MPG.ReNa |
Table of Contents:
- Parkinson's disease (PD) and mitophagy
- Pathogenic mutations in the genes associated with autosomal recessive PD interfere with the mitophagy pathway
- Mitophagy is the selective degradation of damaged mitochondria by autophagy
- Mitophagy allows optimal cellular energy production while it avoids toxic accumulation of damaged mitochondria in neurons