Table of Contents:
  • Mechanism of action of cannabinoid type 1 receptors (CB1)
  • Endocannabinoids (ECBs) and their role as retrograde neurotransmitters
  • The Cre/loxP system
  • CB1 in neurons and in astrocytes
  • CB1 deletion in specific neuronal populations
  • Cannabinoids and working memory via LTD in vivo (NMDAR, AMPAR, neuronal CB1R, astroglial CB1R)
  • Testing working memory (Delayed non-matching to sample T-maze test & Delayed matching to place in Morris water maze)