Amyloid and Related Disorders Surgical Pathology and Clinical Correlations

The second edition of this text presents an overview of the most recent developments in this area including clinical presentation, etiology, pathogenesis, and differential diagnosis. The rationale for various therapies, including transplantation, is discussed and tissue diagnosis (its pitfalls and s...

Full description

Bibliographic Details
Other Authors: Picken, Maria M. (Editor), Herrera, Guillermo A. (Editor), Dogan, Ahmet (Editor)
Format: eBook
Language:English
Published: Cham Humana 2015, 2015
Edition:2nd ed. 2015
Series:Current Clinical Pathology
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
LEADER 04589nmm a2200337 u 4500
001 EB001078519
003 EBX01000000000000000839986
005 00000000000000.0
007 cr|||||||||||||||||||||
008 150908 ||| eng
020 |a 9783319192949 
100 1 |a Picken, Maria M.  |e [editor] 
245 0 0 |a Amyloid and Related Disorders  |h Elektronische Ressource  |b Surgical Pathology and Clinical Correlations  |c edited by Maria M. Picken, Guillermo A. Herrera, Ahmet Dogan 
250 |a 2nd ed. 2015 
260 |a Cham  |b Humana  |c 2015, 2015 
300 |a XIX, 542 p. 391 illus., 345 illus. in color  |b online resource 
505 0 |a Fat tissue analysis in the management of patients with systemic amyloidosis -- Generic diagnosis of amyloid – recent developments and summary of current recommendations -- Amyloid typing on formalin-fixed paraffin sections by immunohistochemistry – experience from two large referral centers -- Options for amyloid typing in renal pathology – the advantages of frozen section immunofluorescence -- Amyloid typing by immuno-electron microscopy -- Classification of amyloidosis by mass spectrometry-based proteomics -- Summary and practical recommendation regarding amyloid typing using antibody-based and proteomic methods -- Ancillary studies of amyloidosis -- Laboratory support for diagnosis of amyloidosis -- Bone marrow biopsy and its utility in the diagnosis of AL amyloidosis and other plasma cell dyscrasias -- Molecular methods for the diagnosis of hereditary amyloidosis --  
505 0 |a Radiologic support for diagnosis and monitoring of amyloidosis – established techniques and recent developments -- Organ involvement inamyloidoses -- Amyloidoses of the Kidney and Genitourinary tract -- Cardiac amyloidosis -- Amyloidosis of the Gastrointestinal tract and Liver -- Peripheral nerve amyloidosis -- Amyloidoses of the Pulmonary and upper respiratory tract -- Amyloidoses involving the skin -- Clinical issues and therapy -- Clinico-pathologic issues in patients with amyloidosis -- Solid organ transplantation in amyloidosis and issues pertaining to domino liver transplantation -- Emerging therapies for amyloidosis -- Clinical trials -- Modern therapies in AA amyloidosis -- Medico legal issues of amyloidosis -- Amyloidosis from the patient’s perspective 
505 0 |a Introduction/general -- Aspects of the history and nomenclature of amyloid and amyloidosis -- Amyloid diseases at the molecular level: general overview and focus on AL amyloidosis -- AA amyloidosis -- Non-Immunoglobulin and non-AA amyloidoses -- The hereditary amyloidoses -- Dialysis-associated amyloidosis -- Localized amyloidoses and amyloidoses associated with aging outside the central nervous system -- Central nervous system amyloid -- Non-amyloid protein deposits -- Differential diagnosis of amyloid in surgical pathology: organized deposits and other material in the differential diagnosis of amyloidosis -- Light /heavy chain deposition disease as a systemic disease -- Glomerulonephritis with non-organized monoclonal immunoglobulin deposits -- Pathologies of renal and systemic intracellular paraprotein storage: crystalopathies and beyond -- Diagnosis -- Diagnosis of amyloid using Congo red – polarized and fluorescence -- Thioflavin T stain for amyloid detection --  
653 |a Nephrology 
653 |a Oncology 
653 |a Pathology 
700 1 |a Herrera, Guillermo A.  |e [editor] 
700 1 |a Dogan, Ahmet  |e [editor] 
041 0 7 |a eng  |2 ISO 639-2 
989 |b Springer  |a Springer eBooks 2005- 
490 0 |a Current Clinical Pathology 
028 5 0 |a 10.1007/978-3-319-19294-9 
856 4 0 |u https://doi.org/10.1007/978-3-319-19294-9?nosfx=y  |x Verlag  |3 Volltext 
082 0 |a 616.07 
520 |a The second edition of this text presents an overview of the most recent developments in this area including clinical presentation, etiology, pathogenesis, and differential diagnosis. The rationale for various therapies, including transplantation, is discussed and tissue diagnosis (its pitfalls and strategies for avoiding them) and laboratory support are included. The involvement of all major organ systems including renal/genitourinary, cardiac, gastrointestinal, pulmonary, peripheral nerve/central nervous system, soft tissue, skin, lymph node/spleen and bone marrow pathology is also covered. Amyloid and Related Disorders, Second Edition will be invaluable to specialized and general pathologists as well as cytopathologists. Other medical professionals may also benefit from this concise update on the systemic amyloidoses