Histone Recognition
This book provides a timely review of the role of histone modifications in epigenetic control of gene expression. Topics covered include: basic mechanisms of molecular recognition of histone post-translational modification (PTMs); combinatorial readout of histone PTMs by tandem epigenome reader doma...
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| Format: | eBook |
| Language: | English |
| Published: |
Cham
Springer International Publishing
2015, 2015
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| Edition: | 1st ed. 2015 |
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| Online Access: | |
| Collection: | Springer eBooks 2005- - Collection details see MPG.ReNa |
Table of Contents:
- The Bromodomain as the Acetyl-Lysine Binding Domain in Gene Transcription
- PHD Fingers as Histone Readers
- Methyl-Lysine Recognition by the Royal Family Modules: Chromo, Tudor, MBT, Chromo Barrel, and PWWP Domains
- Histone Recognition by WD40 Proteins
- Methyl-Lys Recognition by Ankyrin Repeat Proteins
- Methyl-Arginine Recognition by Tudor Domains
- Histone Recognition by Tandem Modules and Modulation by Multiple PTMs
- Genome-Wide Profiling of Molecular Recognition of Histone PTMs
- BET Bromodomain Inhibition as a Therapeutic Approach in Hematological Malignancies
- Anti-Inflammatory Effects of BET Protein Inhibition Through Modulation of Gene Transcription
- Activating Latent HIV by Inhibiting Bromodomain Proteins
- Small Molecule Modulation of Methyl-Lysine Mediated Interactions