Gene Delivery and Therapy for Neurological Disorders

This volume aims to explore the latest developments in adeno-associated viral and lentiviral vectors as well as the gene therapy strategies for the most common neurological disorders, followed by chapters that include step-by-step guides to viral vector-based gene delivery in animal models used in t...

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Bibliographic Details
Other Authors: Bo, Xuenong (Editor), Verhaagen, Joost (Editor)
Format: eBook
Language:English
Published: New York, NY Humana 2015, 2015
Edition:1st ed. 2015
Series:Neuromethods
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • Adeno-Associated Viral Vectors for Gene Delivery to the Nervous System
  • Lentiviral Vectors for Gene Delivery to the Nervous System
  • Gene Therapy for Parkinson’s Disease: AAV-5-Mediated Delivery of Glial Cell Line-Derived Neurotrophic Factor (GDNF)
  • Gene Delivery and Gene Therapy for Alzheimer’s Disease
  • Gene Therapy for Huntington’s Disease
  • Gene Therapy Approaches to Promoting Axonal Regeneration After Spinal Cord Injury
  • Gene Delivery to Neurons of the Dorsal Root Ganglia Using Adeno-Associated Viral Vectors
  • Targeted Gene Therapy for Ischemic Stroke
  • Adeno-Associated Viral Gene Therapy for Retinal Disorders
  • Gene Therapy for Epilepsies
  • AAV Gene Therapy Strategies for Lysosomal Storage Disorders with Central Nervous System Involvement
  • Gene Therapy in Spinal Muscular Atrophy (SMA) Models Using Intracerebroventricular Injection into Neonatal Mice
  • Gene Therapy for Chronic Pain: How to Manipulate and Unravel Pain Control Circuits from the Brain?
  • Gene Therapy Approaches Using Reproducible and Fully Penetrant Lentivirus-Mediated Endogenous Glioma Models