| Summary: | This paper was prepared as background material for a workshop, "Improving the Translation of Research Findings into Clinical Practice: the Potential and Problems of Modern Methods of Clinical Investigation," conducted May 3-4, 1989 by the Committee on Technological Innovation in Medicine of the Institute of Medicine. The observations and conclusions in this publication are solely those of the author. This paper is intended to serve as a background document to this workshop. Its objective is to provide a comparative analysis of present-day evaluative strategies employed in the development of new drugs (Chapter 2), medical devices (Chapter 3), and clinical procedures (Chapter 4). Chapter 5 considers the implications of these strategies for the development process and concludes with some opportunities for improving both the effective and efficient translation of biomedical research findings into clinical practice
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