Computer-assisted modeling contributions of computational approaches to elucidating macromolecular structure and function

In much of biology, the search for understanding the relation between structure and function is now taking place at the macromolecular level. Proteins, nucleic acids, and polysaccharides are macromolecule--polymers formed from families of simpler subunits. Because of their size and complexity, the p...

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Bibliographic Details
Corporate Author: National Research Council (U.S.) Committee on Computer-Assisted Modeling
Format: eBook
Language:English
Published: Washington, D.C. National Academies Press 1987, 1987
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Collection: National Center for Biotechnology Information - Collection details see MPG.ReNa
Description
Summary:In much of biology, the search for understanding the relation between structure and function is now taking place at the macromolecular level. Proteins, nucleic acids, and polysaccharides are macromolecule--polymers formed from families of simpler subunits. Because of their size and complexity, the polymers are capable of both inter- and intramolecular interactions. These interactions confer upon the polymers distinctive three-dimensional shapes. These tertiary configurations, in turn, determine the function of the macromolecule. Computers have become so inextricably involved in empirical studies of three-dimensional macromolecular structure that mathematical modeling, or theory, and experimental approaches are interrelated aspects of a single enterprise
Item Description:Title from PDF title page
Physical Description:1 PDF file (x, 175 pages) illustrations
ISBN:0309568293
9780309568296