Platelet-vessel wall interactions in hemostasis and thrombosis

Platelets are essential mediators of the physiologic process of hemostasis and pathologic thrombosis. While platelets do not interact with vascular walls under normal conditions, vascular injury or inflammation result in a coordinated series of events including platelet adhesion, aggregation, and pr...

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Bibliographic Details
Main Author: Rumbaut, Rolando E.
Other Authors: Thiagarajan, Perumal
Format: eBook
Language:English
Published: [San Rafael, CA] Morgan & Claypool Life Sciences Publishers 2010, c2010
Series:Synthesis lectures on integrated systems physiology : from molecules to function
Subjects:
Online Access:
Collection: National Center for Biotechnology Information - Collection details see MPG.ReNa
Description
Summary:Platelets are essential mediators of the physiologic process of hemostasis and pathologic thrombosis. While platelets do not interact with vascular walls under normal conditions, vascular injury or inflammation result in a coordinated series of events including platelet adhesion, aggregation, and promotion of coagulation. In this review, we describe the primary mechanisms involved in these responses in various vascular beds of both macro- and microvessels, and outline key unresolved aspects of these important interactions
Item Description:Title from PDF t.p. (viewed Aug. 16, 2011)
Physical Description:1 PDF file (viii, 67 p. : ill.)
ISBN:9781615040407
9781615040391