Topical Drug Bioavailability, Bioequivalence, and Penetration

Professor Maibach is a leading authority in the fields of dermatotoxicology and dermatopharmacology, in which he has conducted research and written extensively. John Jenner is a principal scientist at The Defence Science and Technology Laboratory in the UK. He has a degree in pharmacology from the U...

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Bibliographic Details
Other Authors: Shah, Vinod P. (Editor), Maibach, Howard I. (Editor), Jenner, John (Editor)
Format: eBook
Language:English
Published: New York, NY Springer New York 2014, 2014
Edition:2nd ed. 2014
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • 1 Percutaneous Absorption
  • 2 Animal Models for Percutaneous Absorption
  • 3 Mitigating Dermal Exposure to Agrochemicals
  • 4 Importance of In Vitro Drug Release
  • 5 Diffusion Cell Design
  • 6 In Vitro Product Quality Tests and Product Performance Tests for Topical and Transdermal Drug Products
  • 7 Safety and efficacy testing of topical products; Practical considerations
  • 8 Challenges in Evaluating Bioequivalence of Topical Dermatological Drug Products
  • 9 Methods for the Assessment of Bioequivalence of Topical Dosage Forms: Correlations, Optimization Strategies and Innovative Approaches
  • 10 Application of Microdialysis in Assessing Cutaneous Bioavailability
  • 11 Follicular Drug Penetration
  • 12 Development of Pilosebaceous Unit-Targeted Drug Products
  • 13 Deep Percutaneous Penetration into Muscles and Joints: Update
  • 14 Efficacy & Toxicity of Microneedle based devices
  • 15 Mathematical Models for Topical and Transdermal Drug Products
  • 16 Transdermal Patches: An Industrial Perspective on the Relevance of in vitro Skin Permeation Studies and Approaches on Design of Manufacturing Processes
  • 17 Transdermal Drug Delivery Systems.  Regulatory Considerations:  NDA and ANDA Requirements
  • 18 Transdermal Estradiol and Testosterone Transfer in Man: Existence, Models, and Strategies for Prevention
  • 19 Effects of occlusion on dermal drug delivery: implications for bioequivalence measurement
  • 20 Challenges with Clinical Endpoints – Bioequivalence
  • 21 Clinical Considerations of Bioequivalence For Topical Dermatologic Drugs
  • 22 OECD Test Guideline 428 – A method for in vitro percutaneous absorption measurement?
  • 23 Bioequivalence, Quality, and Novel Assessment Technologies for Topical Products: Current Challenges and Future Prospects