Quantitative functional brain imaging with positron emission tomography

This book presents the latest scientific developments in the field of positron emission tomography (PET) dealing with data acquisition, image processing, applications, statistical analysis, tracer development, parameter estimation, and kinetic modeling. It covers improved methodology and the applica...

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Bibliographic Details
Main Author: Carson, Richard Ellis
Other Authors: Daube-Witherspoon, Margaret E., Herscovitch, Peter
Format: eBook
Language:English
Published: San Diego, Calif. Academic Press c1998, 1998
Subjects:
Online Access:
Collection: Elsevier ScienceDirect eBooks - Collection details see MPG.ReNa
Table of Contents:
  • Comparison of Four Populations.
  • M.R. Kilbourn, T.B. Nguyen, S.E. Snyder, and R.A. Koeppe, One For All, Or One For Each? Matching Radiotracers and Regional Brain Pharmacokinetics.
  • A.J. Abrunhosa, F. Brady, S. Luthra, H. Morris, J.J. de Lima, and T. Jones, The Use of Informatin Technology in the Search for New PET Tracers.
  • D. Hussey, J.N. DaSilva, E. Greenwald, K. Cheung, S. Kapur, A.A. Wilson, and S. Houle, Statistical Power Analysis in In Vivo Studies in RatBrain Using PET Radiotracers.
  • A.A. Wilson, T. Inaba, N. Fisher, J.N. DaSilva, and S. Houle, A Human Liver Model of Metabolism as a Tool in the Identification of Potential PET Radiotracers.
  • Includes bibliographical references and index
  • Achieving Computer Platform Independence with Java.
  • Kinetic Modeling:
  • R.A. Koeppe, E.P. Ficaro, D.M. Raffel, S. Minoshima, and M.R. Kilbourn, Temporally Overlapping Dual-Tracer PET Studies.
  • P.J. Toussaint and E. Meyer, Simultaneous Estimation of Perfusion (K1) and Vascular (0) Responses in[<sup>15</sup>O]H2O PET Activation Studies.
  • J.J. Moreno-Cant, C.J. Thompson, E. Meyer, P. Fiset, R.J. Zatorre, D. Klein, and D. Reutens, Enhanc ement of Signal-to-Noise Ration in [<sup>15</sup>O]H2O Bolus PET Activation Studies Using a Combined Cold-bolus/Switched Protocol.
  • Implications for Kinetic Modeling
  • J.C. Matthews, V.J. Cunningham, and P.M. Price, Evaluation of the Contribution of Protocol Design to Model Parameter Uncertainty.
  • D. Ho, D. Feng, and L.C. Wu, An Assessment of Optimal Image Sampling Schedule Design in Dynamic PET-FDG Studies.
  • D. Feng, K.-P. Wong, C.-M. Wu, and W.-C. Siu, Simultaneous Extraction of Physiological and Input Function Parameters from PET Measurement.
  • V.J. Cunningham, R.N. Gunn, H. Byrne, and J.C. Matthews, Suppression of Noise Artifacts in Spectral Analysis of Dynamic PET Data.
  • D.C. Reutens and M. Andermann, Constraints in Spectral Analysis.
  • Technical Aspects and Clinical Results.
  • J.R. Moeller, C. Ghez, A. Antonini, M.F. Ghilardi, V. Dhawan, K. Kazumata, and D. Eidelberg, Brain Networks of Motor Behavior Assessed by Principal Component Analysis.
  • M.S. Vafaee, E. Meyer, S. Marrett, T. Paus, A.C. Evans, and A. Gjedde, Frequency-Dependent Changes in Cerebral Metabolic Rate of Oxygen During Activation of Human Visual Cortex Studied by PET.
  • A.H. Moore, M.J. Raleigh, S.R. Cherry, S.-C. Huang, and M.E. Phelps, Validation of a FDG-PET Protocol in Conscious Vervet Monkey.
  • D.B. Stout, S.C. Huang, M.J. Raleigh, M.E. Phelps, and J.R. Barrio, Comparison of Ketamine/Midazolam Versus Pentobarbital on [<sup>18</sup>F]Fluorodopa PET Kinetics in Monkeys.
  • Methodological Issues.
  • M. Laruelle, A. Abi-Dargham, and R.B. Innis, Imaging Receptor Occupancy by Endogenous Transmitters in Humans.
  • D.F. Wong, T. Solling, F. Yokoi, and A. Gjedde, Quantification of Extracellular Dopamine release in Schizophrenia and Cocaine Use by Means of TREMBLE.
  • BrainPET97 Discussion.
  • Subject Index
  • Preliminary Experience in Patient Studies.
  • A Pet Study with [<sup>11</sup>C] Doxepin.
  • Statistical Analysis:
  • U.E. Ruttimann, D. Rio, R.R. Rawlings, P. Anderson, and D.W. Hommer, PET Analysis Using a Variance Stabilizing Transform.
  • S.R. Cherry, A. Chatziioannou, Y. Shao, R.W> Silverman, K. Meadors, and M.E. Phelps, Brain Imaging in Small Animals with MicroPET.
  • W.W. Moses, P.R.G. Virador, S.E. Derenzo, R.H. Huesman, and T.F. Budinger, Design of a High-Resolution, High-Sensitivity PET Camera for Human Brains and Small Animals.
  • Y. Shao, R. Slates, K. Farahani, A. Bowery, M. Dahlbom, K. Meadors, R.W. Silverman, M. Sugita, and S.R. Cherry, The Road to Simultaneous PET/MR Images of the Brain.
  • D.L. Bailey, M.P. Miller, T.J. Spinks, P.M. Bloomfield, L. Livieratos, R.B. Banati, R. Myers, and T.J. Jones, Brain PET Studies with a High Sensitivity Fully 3D Tomograph.
  • V. Sossi, K.S. Morrison, T.R. Oakes, and T.J. Ruth, Emission-Transmission Realignment Using a Simultaneous Emission-Transmission Postinjection Scan.
  • 6-[<sup>18</sup>F]Fluoro-L-DOPA vs. 6-[<sup>18</sup>F]Fluoro-L-M-Tyrosine.
  • S. Nagatsuka, H. Namba, M. Iyo, K. Fukushi, H. Shinotoh, T. Suhara, Y. Sudo, K. Suzuki, and T. Irie, Quantitative Measurement of Acetylcholinesterase Activity in Living Human Brain Using a Radioactive Acetylcholine Analog and Dynamic PET.
  • R.N. Gunn, A.A. Lammertsa, and V.J. Cunningham, Parametric Imaging of Ligand-Receptor Interactions Using a Reference Tissue Model and Cluster Analysis.
  • E.D. Morris, S.I. Chefer, and E.D. London, Limitations of Binding Potential asa Measure of Receptor Function. A Two-Point Correction for the Effects of Mass.
  • Examination of Nonspecific Component.
  • C.J. Endres and R.E. Carson, Characteristics of Neurotransmitter Competition Studies Using Constant Infusion of Tracer.
  • J.C. Price, N.S. Mason, B. Lopresti, D. Holt, N.R. Simpson, W. Drevets, G.S. Smith, and C.A. Mathis, PET Measurement of Endogenous Neurotransmitter Activity Using High and Low Affinity Radiotracers.
  • R. Graf, A. Schuster, J. Littgen, U. Pietrzyk, K. Ohta, E. Kumura, K. Weinhard, and W.-D. Heiss, Sequential Experimental PET: Voxel Based Analysis Reveals Spatiotemporal Dynamics of Perfusion in Transient Focal Cerebral Ischemia.
  • J. Littgen, U. Pietrzyk, K. Herholz, K. Wienhard, and W.-D. Heiss, Estimation of Ischemic CBF Using [<sup>15</sup>O]H2O and PET Without Arterial Blood Sampling.
  • A. Thiel, K. Herholz, H.-M. von Stockhausen, G. Pawlik, and W.-D. Heiss, Suitability of [<sup>15</sup>O]H2O and PET to Detect Activation-Induced CBF Changes in Brain Tissue Altered by Brain Tumors.
  • S.C. Huang, J. Yang, C.L. Yu, and K.P. Lin, Performance Characterization of a Feature-Matching Axial Smoothing Method for Brain PET Images.
  • J.L.R. Anderson, Registration of Multitracer PET Data.
  • O.R. Mawlawi, B.J. Beattie, S.M. Larson, and R.G. Blasberg, Multimodality Brain Image Registration Using a 3-D Photogrammetrically Derived Surface.
  • J. Yap, V. Cunningham, T. Jones, M. Cooper, C.T. Chen, and P. Price, Classification of Dynamic PET Images Using A Priori Kinetic Factors.
  • J.R. Rakshi, D.L. Bailey, K. Ito, T. Uema, P.K. Morrish, J. Ashburner, K.J. Friston, and D.J. Brooks, Methodology for Statistical Parametric Mapping of [<sup>18</sup>F]Fluorodopa Uptake Rate Using 3D PET.
  • H. Litt and B. Horwitz, The Use of Nonlinear Kernal Analysis to Evaluate The Badness-of-Fit of the Transformation of PET Images Into Stereotactic Space: Application to Alzheimers Disease.
  • Sect. I. Data acquisition and quantification
  • Sect. II. Image processing
  • Sect. III. Applications
  • Sect. IV. Statistical analysis
  • Sect. V. Tracer development
  • Sect. VI. Parameter estimation
  • Sect. VII. Kinetic modeling
  • Sect. VIII. BRAINPET97 discussion