RNA Interference Challenges and Therapeutic Opportunities

RNA Interference: Challenges and Therapeutic Opportunities provides readers with recent advances in siRNA design, delivery, targeting, and methods to minimize siRNA’s unwanted effects. Preclinical and clinical use of synthetic siRNAs, the roles of miRNAs in cancer, and the promise of extracellular m...

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Bibliographic Details
Other Authors: Sioud, Mouldy (Editor)
Format: eBook
Language:English
Published: New York, NY Humana 2015, 2015
Edition:1st ed. 2015
Series:Methods in Molecular Biology
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Description
Summary:RNA Interference: Challenges and Therapeutic Opportunities provides readers with recent advances in siRNA design, delivery, targeting, and methods to minimize siRNA’s unwanted effects. Preclinical and clinical use of synthetic siRNAs, the roles of miRNAs in cancer, and the promise of extracellular miRNAs for diagnosis are also covered in this meticulous collection, along with novel methods for identifying endogenous siRNAs and the annotation of small RNA transcriptomes. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory.   Comprehensive and cutting-edge, RNA Interference: Challenges and Therapeutic Opportunities will aid researchers, clinicians, teachers, and biotechnologists interested in the power of RNA-based therapies
Physical Description:XVI, 495 p. 108 illus., 58 illus. in color online resource
ISBN:9781493915385