Ras Superfamily Small G Proteins: Biology and Mechanisms 1 General Features, Signaling
This first of two volumes provides a general overview of the genetics, structure, mechanism and regulation of the Ras superfamily proteins and describes in detail the signaling pathways and processes regulated by specific members of this family. The focus of this first volume is on the Rho and Ras s...
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| Format: | eBook |
| Language: | English |
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Vienna
Springer Vienna
2014, 2014
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| Edition: | 1st ed. 2014 |
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| Online Access: | |
| Collection: | Springer eBooks 2005- - Collection details see MPG.ReNa |
Table of Contents:
- Evolution of the Ras Superfamily of GTPases
- The structure of the G domain of the Ras superfamily
- GEFs and GAPs: Mechanisms and Structures
- Bacterial protein toxins acting on small GTPases
- Posttranslational modifications of small G proteins
- Targeting the Raf-MEK-ERK Mitogen-Activates Protein Kinase Cascade for the Treatment of RAS Mutant Cancers
- RAS Genes and Cancer
- The Spatial Organization of Ras Signaling
- Ras Nanoclusters
- Mouse Models of Ras induced Tumors and Developmental Disorders
- Rap signaling
- The coordinated biology and signaling partners of Ral G-proteins
- Structure and Function of the mTOR Activator Rheb
- Classical Rho proteins: Biochemistry of molecular switch function and regulation
- Atypical Rho family members
- Molecular Structures, Cellular Functions and Physiological Roles of Rho Effectors
- Principles driving the spatial organization of Rho GTPase signaling at synapses
- Rho GTPases in Cancer