MACPF/CDC Proteins - Agents of Defence, Attack and Invasion
This book focusses on evolutionary, structural and functional aspects of pore-forming proteins, bringing together prominent researchers in the fields of structural biology and cellular and biophysical techniques. The focus is on the MACPF/CDC protein superfamily that was originally discovered becaus...
| Other Authors: | , |
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| Format: | eBook |
| Language: | English |
| Published: |
Dordrecht
Springer Netherlands
2014, 2014
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| Edition: | 1st ed. 2014 |
| Series: | Subcellular Biochemistry
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| Subjects: | |
| Online Access: | |
| Collection: | Springer eBooks 2005- - Collection details see MPG.ReNa |
Table of Contents:
- Part I: Overview of MACPF/CDCs
- Introduction: Brief Historical Overview
- Distribution of MACPF/CDC proteins
- Evolution of the Complement System
- Part II: Structures of MACPF/CDCs
- Structural Features of Cholesterol Dependent Cytolysins and Comparison to other MACPF-domain containing proteins
- Perfringolysin O Structure and Mechanism of Pore Formation as a Paradigm for Cholesterol-Dependent Cytolysins
- Structural Biology of the Membrane Attack Complex
- Part III: Functional aspect
- Membrane Interactions and Cellular Effects of MACPF/CDC Proteins
- The Biology of Pneumolysin
- Multifaceted Activity of Listeriolysin O, the Cholesterol-Dependent Cytolysin of Listeria monocytogenes
- Perforin - a Key Pore-Forming Protein for Immune Control of Viruses and Cancer
- Perforin and Human Diseases
- The role of MACPF Proteins in the Biology of Malaria and other Apicomplexan Parasites
- Chlamydial MACPF Protein CT153
- Fungal MACPF-Like Proteins and Aegerolysins: Bi-Component Pore-Forming Proteins?
- Fluorescence Imaging of MACPF/CDC Proteins: New Techniques and Their Application