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SCF and APC E3 Ubiquitin Ligases in Tumorigenesis

This SpringerBrief explores the physiological roles of Skp1-Cullin1-F-box Complex (SCF) and Anaphase Promoting Complex (APC) in normal cells and in tumor formation. These two related, multi-subunit E3 ubiquitin ligase enzymes, APC and SCF are thought to be the major driving forces governing proper c...

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Bibliographic Details
Main Authors: Inuzuka, Hiroyuki, Wei, Wenyi (Author)
Format: eBook
Language:English
Published: Cham Springer International Publishing 2014, 2014
Edition:1st ed. 2014
Series:SpringerBriefs in Cancer Research
Subjects:
Proteins
Cytological Techniques
Cancer
Cytology / Technique
Cancer Biology
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • 1. Introduction
  • 2. The Fbxw subclass of SCF E3 ubiquitin Ligases
  • 3. The FbxL subclass of SCF E3 ubiquitin Ligases
  • 4. The Fbxo subclass of SCF E3 ubiquitin Ligases
  • 5. APC/Cdc20 and APC/Cdh1 E3 ubiquitin Ligases
  • 6. Conclusions and Future Perspectives

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