Nanoscale Imaging of Synapses New Concepts and Opportunities
Synapses underlie rapid and flexible neural communication in the brain and they hold the key to understanding higher brain functions in health and disease. Because they are very small and highly dynamic, it is very difficult to study them with traditional techniques. Fortunately, recent ground-break...
| Other Authors: | , |
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| Format: | eBook |
| Language: | English |
| Published: |
New York, NY
Humana
2014, 2014
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| Edition: | 1st ed. 2014 |
| Series: | Neuromethods
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| Subjects: | |
| Online Access: | |
| Collection: | Springer eBooks 2005- - Collection details see MPG.ReNa |
Table of Contents:
- Preface
- Nanoscale imaging of protein molecules at the postsynaptic densit
- Electron tomography for the study of synaptic ultrastructure in fixed brain sections
- Time-resolved electron microscopy: coupling optogenetics with high-pressure freezing
- Investigating AMPA receptors diffusion and nanoscale organization at synapses with high density single molecule tracking methods
- Visualising the ultra-structures and dynamics of synapses by single molecule nanoscopy
- Live-cell PALM of intracellular proteins in neurons
- Monitoring nanoscale mobility of small molecules with time-resolved fluorescence anisotropy imaging
- Imaging signalling transduction in single dendritic spines
- Imaging-based measures of synaptic tenacity
- Zooming in on the (peri)synaptic extracellular matrix
- Two-photon STED microscopy for imaging synapses and glia in acute brain slices
- Index