Radionuclide Imaging in Drug Research

The use of gamma-emitting radionuclides for diagnostic imaging in nuclear medicine has been established for many years. Sophisticated gamma ray detecting camera systems and computer links enable the clinical investigator to image different regions of the body and to quantify organ function. Parallel...

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Bibliographic Details
Other Authors: Wilson, Clive G. (Editor)
Format: eBook
Language:English
Published: Dordrecht Springer Netherlands 1982, 1982
Edition:1st ed. 1982
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • 16. In Vivo Distributions of 99mTc-Labelled Liposomes
  • 17. Factors Influencing the Clearance Rates of Colloidal Particles from the Rabbit Knee Joint
  • 18. The Distribution of Radiolabelled Drug in Animals Infected with Cutaneous Leishmaniasis: Comparison of Free and Liposome-Bound Sodium Stibogluconate
  • 19. Poster Abstracts
  • 19.1 (1-11C)-Acetate — An Agent for the Tomographic Study of Myocardial Metabolism
  • 19.2 Bone Scanning in Breast Cancer: Identification of the High-Risk Patient to Increase Positive Yield
  • 19.3 Analysis of Gastric Emptying: a Standardised Technique
  • 19.4 Intestinal Transit Time of 51Cr-Labelled Pellets of Different Densities
  • 19.5 Deposition of Cobalt-57 in the Rat
  • 19.6 Studies on the Systemic Bioavailability of Buprenorphine by Various Routes of Administration
  • 19.7 The Clearance of Liposomes Administered by theIntramuscular Route
  • 19.8 The Clearance of Polystyrene Microspheres from an Intramuscular Injection Site
  • 19.9 The Clearance of Albumin Microspheres from an Intramuscular Injection Site
  • 19.10 Gastric Emptying of Oils in the Rat
  • 19.11 Evaluation of an Oral Sustained-Release Preparation by Gamma Scintigraphy
  • 19.12 Spreading of Suppository Bases Assessed with Histological and Scintigraphic Techniques
  • 19.13 Studies on Microencapsulation using Radionuclides
  • 1. Dosage Design — Past, Present and Future
  • 2. Radiopharmaceutical Targeting in Nuclear Medicine
  • 3. Data Handling and Computation in Radionuclide Studies
  • 4. Choice of Radionuclides for Scintigraphy
  • 5. Formulation of Radiopharmaceuticals
  • 6. Quality Control of Radiopharmaceuticals
  • 7. Radiopharmaceutical Distribution Studies in the Rat
  • 8. Studies of Radiolabelled Preparations in the Rabbit
  • 9. The Utilisation of Short-Lived Radionuclides in the Assessment of Formulation and In Vivo Disposition of Drugs
  • 10. Gastrointestinal Transit of Gamma-Emitting Radionuclide Labelled Preparations
  • 11. Use of Multiple Pinhole External Scintigraphy to Monitor Tablet Disintegration in Vivo
  • 12. Spreading Characteristics of Proprietary Rectal Steroid Preparations
  • 13. In Vivo Radioimmunodetection of Cancer
  • 14. Therapeutic Aerosol Deposition
  • 15. The Evaluation of Parenterally Administered Emulsion Formulations